:root{color-scheme:light;--header-height: 4.75rem;--shell: min(72rem, calc(100vw - 4rem))}*,*::before,*::after{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:calc(var(--header-height) + 2rem)}body{margin:0;background:#f4f1ea;color:#171717;font-family:"Helvetica Neue","Avenir Next",Avenir,Helvetica,Arial,sans-serif;font-size:1rem;line-height:1.55;-webkit-font-smoothing:antialiased}body.nav-open{overflow:hidden}img,svg{display:block;max-width:100%}a{color:inherit;text-decoration-thickness:0.08em;text-underline-offset:0.16em}button,input,textarea,select{font:inherit}button,a{-webkit-tap-highlight-color:transparent}::selection{background:#7765e3;color:#fffdf8}:focus-visible{outline:3px solid #7765e3;outline-offset:4px}h1,h2,h3,p,blockquote{margin-top:0}h1,h2,h3{font-weight:500;letter-spacing:-0.045em;line-height:0.98}h1{font-size:clamp(2.75rem, 5.75vw, 5.75rem)}h2{font-size:clamp(1.85rem, 3.65vw, 3.9rem)}h3{font-size:clamp(1.35rem, 1.7vw, 1.85rem)}.shell{width:var(--shell);margin-inline:auto}.section{padding-block:clamp(3.85rem, 7vw, 7rem)}.eyebrow{margin-bottom:1.25rem;font-size:0.78rem;font-weight:700;letter-spacing:0.15em;line-height:1.3;text-transform:uppercase}.sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0, 0, 0, 0);white-space:nowrap;border:0}.skip-link{position:fixed;top:0.75rem;left:0.75rem;z-index:100;padding:0.7rem 1rem;border-radius:999px;background:#171717;color:#fffdf8;transform:translateY(-180%)}.skip-link:focus{transform:translateY(0)}.reveal{opacity:1;transform:none}.js .reveal{opacity:0;transform:translateY(1.75rem);transition:opacity 700ms ease,transform 700ms cubic-bezier(0.22, 1, 0.36, 1)}.js .reveal.is-visible{opacity:1;transform:translateY(0)}@media (prefers-reduced-motion: reduce){html{scroll-behavior:auto}*,*::before,*::after{animation-duration:0.01ms !important;animation-iteration-count:1 !important;transition-duration:0.01ms !important}.js .reveal{opacity:1;transform:none}}@media (max-width: 760px){:root{--header-height: 4rem;--shell: calc(100vw - 2rem)}h1{font-size:clamp(2.35rem, 10.5vw, 3.5rem)}h2{font-size:clamp(1.9rem, 8.5vw, 2.8rem)}.section{padding-block:3.5rem}}.site-header{position:relative;z-index:50;height:var(--header-height);background:#f4f1ea}.header-inner{display:flex;align-items:center;justify-content:space-between;height:100%;border-bottom:1px solid rgba(23,23,23,0.16)}.wordmark{display:inline-flex;gap:0.7rem;align-items:center;font-size:1.1rem;font-weight:650;letter-spacing:-0.025em;text-decoration:none}.movement-mark{position:relative;display:block;width:1.9rem;height:0.95rem;flex:0 0 auto}.movement-mark i{position:absolute;display:block;height:1.5px;border-radius:2px;background:currentColor;transform:rotate(var(--angle));transform-origin:left center}.movement-mark i:nth-child(1){top:8px;left:0;width:4px;--angle: 0deg}.movement-mark i:nth-child(2){top:8px;left:4px;width:6.4px;--angle: -51deg}.movement-mark i:nth-child(3){top:3px;left:8px;width:8.5px;--angle: 69deg}.movement-mark i:nth-child(4){top:11px;left:11px;width:6.4px;--angle: -51deg}.movement-mark i:nth-child(5){top:6px;left:15px;width:4.5px;--angle: 27deg}.movement-mark i:nth-child(6){top:8px;left:19px;width:5.8px;--angle: -31deg}.movement-mark i:nth-child(7){top:5px;left:24px;width:6.3px;--angle: 18deg}.site-nav{display:flex;gap:clamp(1.2rem, 2.5vw, 2.5rem);align-items:center}.site-nav>a:not(.button){position:relative;font-size:0.9rem;font-weight:520;text-decoration:none}.site-nav>a:not(.button)::after{position:absolute;right:0;bottom:-0.35rem;left:0;height:1px;background:currentColor;content:"";transform:scaleX(0);transform-origin:right;transition:transform 220ms ease}.site-nav>a:hover::after,.site-nav>a[aria-current="page"]::after{transform:scaleX(1);transform-origin:left}.nav-toggle{display:none}.button{display:inline-flex;gap:0.65rem;align-items:center;justify-content:center;min-height:3.15rem;padding:0.8rem 1.35rem;border:1px solid #171717;border-radius:999px;background:#171717;color:#fffdf8;font-size:0.88rem;font-weight:650;text-decoration:none;transition:background 180ms ease, color 180ms ease, transform 180ms ease}.button:hover{background:transparent;color:#171717;transform:translateY(-2px)}.button-small{min-height:2.65rem;padding:0.65rem 1.1rem}.button-light{border-color:#fffdf8;background:#fffdf8;color:#1d1b23}.button-light:hover{background:transparent;color:#fffdf8}.text-link{display:inline-flex;gap:0.55rem;align-items:center;font-size:0.88rem;font-weight:700;text-decoration:none}.text-link span{transition:transform 180ms ease}.text-link:hover span{transform:translateX(0.3rem)}.text-link-light{color:#fffdf8}.hero{padding-block:clamp(4rem, 7vw, 7.5rem) clamp(5rem, 9vw, 9rem);overflow:hidden}.hero-grid{display:grid;grid-template-columns:minmax(0, 1.35fr) minmax(22rem, 0.65fr);gap:clamp(3rem, 8vw, 9rem);align-items:center}.hero-copy h1{max-width:11ch;margin-bottom:2.3rem}.hero-copy h1 em{position:relative;color:#5544c4;font-family:Iowan Old Style,Baskerville,"Times New Roman",serif;font-weight:400}.hero-deck{max-width:44rem;margin-bottom:2.5rem;color:#4c4944;font-size:clamp(1.1rem, 1.55vw, 1.42rem);line-height:1.45}.hero-actions{display:flex;gap:1.6rem;align-items:center;flex-wrap:wrap}.hero-signal{position:relative;min-height:clamp(22rem, 34vw, 32rem);padding:2rem;border-radius:2.25rem;background:#7765e3;color:#fffdf8;overflow:hidden}.signal-meta{position:relative;z-index:2;display:flex;justify-content:space-between;font-size:0.66rem;font-weight:700;letter-spacing:0.12em}.motion-plot{position:absolute;top:5.5rem;right:2rem;bottom:9.5rem;left:2rem;border-block:1px solid rgba(255,255,255,0.28);background-image:linear-gradient(to bottom, transparent 33.2%, rgba(255,255,255,0.16) 33.3%, transparent 33.5%, transparent 66.5%, rgba(255,255,255,0.16) 66.6%, transparent 66.8%),repeating-linear-gradient(to right, rgba(255,255,255,0.13) 0, rgba(255,255,255,0.13) 1px, transparent 1px, transparent 12.5%)}.motion-plot canvas{position:absolute;inset:0;width:100%;height:100%}.axis-legend{position:absolute;top:0;bottom:0;left:0.45rem;display:grid;grid-template-rows:repeat(3, 1fr);align-items:center;color:rgba(255,255,255,0.6);font-family:Iowan Old Style,Baskerville,"Times New Roman",serif;font-size:0.72rem;font-style:italic}.activity-regions{position:absolute;right:0;bottom:-1.8rem;left:0;display:grid;grid-template-columns:0.85fr 0.75fr 1.3fr 1fr;color:rgba(255,255,255,0.48);font-size:0.58rem;letter-spacing:0.1em;text-transform:uppercase}.activity-regions span{padding-left:0.4rem;border-left:1px solid rgba(255,255,255,0.3)}.signal-caption{position:absolute;right:2rem;bottom:2rem;left:2rem;display:flex;align-items:end;justify-content:space-between;padding-top:1rem;border-top:1px solid rgba(255,255,255,0.45)}.signal-caption strong{font-size:clamp(2rem, 4vw, 4rem);font-weight:500;letter-spacing:-0.05em;line-height:1}.signal-caption span{max-width:9rem;font-size:0.75rem;line-height:1.3;text-align:right}@media (min-width: 981px){.signal-caption{gap:1rem}.signal-caption strong{font-size:clamp(2rem, 3vw, 3rem);white-space:nowrap}.signal-caption span{flex:0 1 7.5rem}}.metrics-band{border-block:1px solid rgba(23,23,23,0.16)}.metrics-grid{display:grid;grid-template-columns:repeat(4, 1fr)}.metrics-grid div{display:flex;min-height:8.5rem;padding:1.6rem;flex-direction:column;justify-content:space-between;border-right:1px solid rgba(23,23,23,0.16)}.metrics-grid div:first-child{border-left:1px solid rgba(23,23,23,0.16)}.metrics-grid strong{font-size:clamp(1.65rem, 2.6vw, 2.5rem);font-weight:500;letter-spacing:-0.045em}.metrics-grid span{color:#6d6a64;font-size:0.8rem}.section-heading{display:grid;grid-template-columns:minmax(0, 1.35fr) minmax(18rem, 0.65fr);gap:4rem;align-items:end;margin-bottom:clamp(4rem, 7vw, 7rem)}.section-heading h2{margin-bottom:0}.section-heading>p{max-width:31rem;margin-bottom:0.5rem;color:#6d6a64;font-size:1.05rem}.compact-heading{align-items:center}.project-list{display:grid;gap:clamp(5rem, 9vw, 10rem)}.landscape-grid{display:grid;grid-template-columns:repeat(2, minmax(0, 1fr));gap:1rem}.landscape-card,.detail-card{margin:0}.landscape-card{padding:clamp(1.5rem, 3vw, 2.75rem);border:1px solid rgba(23,23,23,0.16);border-radius:2.25rem;background:rgba(255,253,248,0.48)}.landscape-card header,.detail-card header{display:flex;align-items:baseline;justify-content:space-between;gap:2rem}.landscape-card h3,.detail-card h3{margin-bottom:0;font-size:clamp(1.8rem, 3vw, 3rem)}.chart-index{margin-bottom:0;color:#6d6a64;font-size:0.65rem;font-weight:700;letter-spacing:0.11em;text-transform:uppercase}.landscape-chart{position:relative;height:clamp(21rem, 34vw, 29rem);padding:3rem 1.5rem 3.4rem 3.4rem;margin-top:2rem}.landscape-plot{position:relative;width:100%;height:100%;border-bottom:1px solid rgba(23,23,23,0.4);border-left:1px solid rgba(23,23,23,0.4);background-image:repeating-linear-gradient(to bottom, rgba(23,23,23,0.16) 0, rgba(23,23,23,0.16) 1px, transparent 1px, transparent 50%),repeating-linear-gradient(to right, rgba(23,23,23,0.16) 0, rgba(23,23,23,0.16) 1px, transparent 1px, transparent 50%)}.landscape-y-label,.landscape-x-label{position:absolute;color:#6d6a64;font-size:0.62rem;font-weight:700;letter-spacing:0.06em;text-transform:uppercase}.landscape-y-label{top:50%;left:-5rem;width:14rem;text-align:center;transform:rotate(-90deg)}.landscape-x-label{right:0;bottom:0;left:3.4rem;text-align:center}.landscape-y-ticks{position:absolute;top:3rem;bottom:3.4rem;left:0;display:flex;flex-direction:column;justify-content:space-between;color:#6d6a64;font-size:0.65rem;text-align:right}.landscape-x-ticks{position:absolute;right:1.5rem;bottom:2rem;left:3.4rem;height:0.8rem;color:#6d6a64;font-size:0.65rem}.landscape-x-ticks span{position:absolute;top:0;left:var(--tick-x);transform:translateX(-50%)}.landscape-point{position:absolute;top:var(--point-y);left:var(--point-x);z-index:2;display:flex;align-items:center;flex-direction:column;transform:translate(-50%, -50%);white-space:nowrap}.landscape-point i{display:block;width:0.9rem;height:0.9rem;margin-bottom:0.6rem;border-radius:50%;box-shadow:0 0 0 0.38rem rgba(23,23,23,0.08)}.landscape-point b{font-size:0.72rem;font-weight:700}.landscape-point small{color:#6d6a64;font-size:0.62rem}.landscape-point-sensori i{background:#5544c4;box-shadow:0 0 0 0.4rem rgba(119,101,227,0.2)}.landscape-point-sensori b{color:#5544c4}.landscape-point-prior i{border:1.5px solid #6d6a64;background:#f4f1ea}.landscape-card figcaption,.detail-card figcaption{padding-top:1.25rem;border-top:1px solid rgba(23,23,23,0.16);color:#6d6a64;font-size:0.72rem;line-height:1.55}.landscape-notes{display:grid;grid-template-columns:auto auto 1fr;gap:1rem 2rem;align-items:start;padding:1.2rem 0 0;color:#6d6a64;font-size:0.68rem}.landscape-notes p{margin-bottom:0}.landscape-notes p:last-child{text-align:right}.landscape-notes a{color:#171717}.legend-dot{display:inline-block;width:0.52rem;height:0.52rem;margin-right:0.45rem;border-radius:50%}.legend-dot-sensori{background:#5544c4}.legend-dot-prior{border:1px solid #6d6a64}.evidence-heading{display:grid;grid-template-columns:0.45fr 1.55fr;gap:2rem;align-items:end;padding-top:clamp(5rem, 9vw, 9rem);margin-bottom:2.5rem;border-bottom:1px solid rgba(23,23,23,0.16)}.evidence-heading h3{max-width:22ch;margin-bottom:1.4rem;font-size:clamp(2.3rem, 4.3vw, 4.5rem);text-wrap:balance}@media (min-width: 981px){.evidence-heading{grid-template-columns:auto minmax(0, 1fr)}.evidence-heading h3{max-width:none;font-size:clamp(2.3rem, 3.6vw, 3.8rem);white-space:nowrap}}.result-grid{display:grid;grid-template-columns:repeat(2, minmax(0, 1fr));gap:1rem}.result-card{display:flex;min-height:clamp(21rem, 29vw, 26rem);padding:clamp(1.75rem, 3vw, 3rem);flex-direction:column;justify-content:space-between;border-radius:2.25rem}.result-card-coral{background:#f47f64}.result-card-violet{background:#7765e3;color:#fffdf8}.result-card-blue{background:#5f98d6}.result-card-lime{background:#b7d66b}.result-label{margin-bottom:0.7rem;font-size:0.64rem;font-weight:750;letter-spacing:0.12em;text-transform:uppercase}.result-number{margin-bottom:4rem;font-size:clamp(5rem, 10vw, 10rem);font-weight:450;letter-spacing:-0.08em;line-height:0.78}.result-number small{font-size:0.42em;font-weight:inherit}.result-number-paired{display:grid;grid-template-columns:repeat(2, minmax(0, 1fr));gap:1rem;font-size:clamp(2.6rem, 5vw, 5.25rem)}.result-number-paired span,.result-number-paired small{display:block}.result-number-paired small{margin-top:0.7rem;font-family:"Helvetica Neue","Avenir Next",Avenir,Helvetica,Arial,sans-serif;font-size:0.16em;font-weight:700;letter-spacing:0.14em;text-transform:uppercase}.result-card h3{margin-bottom:1rem}.result-card div>p{max-width:31rem;margin-bottom:0;opacity:0.72}.comparison-key{display:grid;gap:0.55rem;margin-bottom:4rem}.comparison-key span{display:grid;grid-template-columns:1.1rem minmax(0, auto) 1fr;gap:0.7rem;align-items:center;min-height:2.6rem;padding:0.45rem 0.8rem;border:1px solid rgba(23,23,23,0.3);border-radius:999px}.comparison-key i{width:0.6rem;height:0.6rem;border-radius:50%;background:#171717}.comparison-key b{font-size:0.74rem}.comparison-key small{color:rgba(23,23,23,0.58);font-size:0.66rem;text-align:right}.trait-composition{display:flex;gap:0.45rem;height:7.6rem;margin-bottom:4rem}.trait-composition span{display:flex;min-width:0;padding:1rem;flex:var(--trait-size);flex-direction:column;justify-content:space-between;border:1px solid rgba(255,253,248,0.5);border-radius:1.25rem}.trait-composition b{font-size:2rem;font-weight:500;line-height:1}.trait-composition small{color:rgba(255,253,248,0.7);font-size:0.65rem}.cohort-connections{display:grid;grid-template-columns:1fr 2rem 1fr 2rem 1fr;align-items:center;margin-bottom:4rem}.cohort-connections>i{height:1px;background:rgba(23,23,23,0.38)}.cohort-country{position:relative;display:flex;min-height:7rem;padding:1rem 0.65rem;flex-direction:column;justify-content:space-between;border:1px solid rgba(23,23,23,0.32);border-radius:1.25rem;text-align:center}.cohort-country::before{position:absolute;top:-0.35rem;left:calc(50% - 0.35rem);width:0.7rem;height:0.7rem;border:1px solid rgba(23,23,23,0.45);border-radius:50%;background:#5f98d6;content:""}.cohort-country b{font-size:0.72rem;line-height:1.2}.cohort-country small{color:rgba(23,23,23,0.62);font-size:0.66rem}.disease-pair{display:grid;gap:1.25rem;margin-bottom:4rem}.disease-pair>div{display:grid;grid-template-columns:minmax(7rem, 1fr) auto;gap:0.35rem 1.2rem;align-items:center}.disease-pair span{position:relative;grid-row:1 / span 2;height:1.25rem;border:1px solid rgba(23,23,23,0.28);border-radius:999px;overflow:hidden}.disease-pair span::after{position:absolute;inset:0 auto 0 0;width:var(--fraction);border-radius:inherit;background:#171717;content:""}.disease-pair b{font-size:1.45rem;font-weight:550;letter-spacing:-0.04em;line-height:1}.disease-pair small{color:rgba(23,23,23,0.62);font-size:0.64rem;text-transform:uppercase}.closer-section{border-block:1px solid rgba(23,23,23,0.16);background:#fffdf8}.closer-grid{display:grid;grid-template-columns:repeat(2, minmax(0, 1fr));gap:1rem}.detail-card{display:flex;min-height:42rem;padding:clamp(1.5rem, 3vw, 2.75rem);flex-direction:column;border-radius:2.25rem;background:#f4f1ea}.detail-card figcaption{margin-top:auto}.detail-card-har{background:rgba(244,127,100,0.24)}.detail-card-cohort{background:rgba(95,152,214,0.2)}.benchmark-key{display:flex;justify-content:space-between;gap:1rem;margin:4rem 0 1rem;color:#6d6a64;font-size:0.66rem}.benchmark-key span{display:flex;gap:0.4rem;align-items:center}.benchmark-key i{width:0.55rem;height:0.55rem;border-radius:50%;background:#f47f64}.benchmark-list{margin-bottom:3rem;border-top:1px solid rgba(23,23,23,0.16)}.benchmark-list>div{display:grid;grid-template-columns:7.8rem minmax(5rem, 1fr) 6.7rem;gap:1rem;align-items:center;min-height:4.8rem;border-bottom:1px solid rgba(23,23,23,0.16)}.benchmark-list span{display:flex;align-items:baseline;justify-content:space-between;gap:0.5rem;font-size:0.75rem;font-weight:700}.benchmark-list span small{color:#6d6a64;font-size:0.62rem;font-weight:600}.benchmark-list>div>i{position:relative;display:block;height:0.42rem;border-radius:999px;background:rgba(23,23,23,0.1);overflow:hidden}.benchmark-list>div>i b{position:absolute;inset:0 auto 0 0;width:var(--score);border-radius:inherit;background:#f47f64}.benchmark-list strong{font-size:0.78rem;font-weight:700;text-align:right}.benchmark-list strong small{color:#6d6a64;font-size:0.64rem;font-weight:500}.cohort-matrix{margin:4rem 0 3rem;border-top:1px solid rgba(23,23,23,0.16)}.matrix-row{display:grid;grid-template-columns:1.05fr repeat(3, 1fr);align-items:stretch;border-bottom:1px solid rgba(23,23,23,0.16)}.matrix-row>*{display:flex;min-width:0;min-height:4.4rem;padding:0.8rem;align-items:center;justify-content:center;border-left:1px solid rgba(23,23,23,0.16);font-size:0.85rem;font-weight:600}.matrix-row>*:first-child{justify-content:flex-start;border-left:0}.matrix-head>*{min-height:3.6rem;flex-direction:column;color:#6d6a64;font-size:0.66rem;font-weight:700}.matrix-head small{font-size:0.56rem;font-weight:500}.matrix-row .metric-sex{background:rgba(119,101,227,0.14)}.matrix-row .metric-age{background:rgba(244,127,100,0.16)}.matrix-row .metric-bmi{background:rgba(95,152,214,0.17)}.detail-card-disease{display:grid;grid-column:1 / -1;grid-template-columns:minmax(16rem, 0.65fr) minmax(0, 1.35fr);gap:clamp(3rem, 8vw, 8rem);min-height:30rem;align-items:center;background:#b7d66b}.disease-copy header{display:block}.disease-copy .chart-index{margin-bottom:1rem}.disease-copy>p{max-width:28rem;margin-top:2rem;color:rgba(23,23,23,0.7)}.disease-copy .disease-caveat{padding-top:1rem;border-top:1px solid rgba(23,23,23,0.25);font-size:0.72rem}.delta-plot{padding:clamp(1.5rem, 3vw, 2.5rem);border:1px solid rgba(23,23,23,0.22);border-radius:1.25rem;background:rgba(255,253,248,0.38)}.delta-axis{display:flex;justify-content:space-between;padding-left:9.6rem;color:#6d6a64;font-size:0.62rem}.delta-row{display:grid;grid-template-columns:8.5rem minmax(8rem, 1fr) 4.4rem;gap:1.1rem;align-items:center;min-height:5.3rem}.delta-row>span{font-size:0.72rem;font-weight:650}.delta-row>i{position:relative;display:block;height:1px;background:rgba(23,23,23,0.36)}.delta-row>i::before,.delta-row>i::after{position:absolute;top:-0.28rem;width:1px;height:0.55rem;background:rgba(23,23,23,0.28);content:""}.delta-row>i::before{left:25%}.delta-row>i::after{right:auto;left:75%}.delta-row>i b{position:absolute;top:-0.42rem;left:var(--delta, 0%);width:0.85rem;height:0.85rem;border-radius:50%;background:#171717;transform:translateX(-50%)}.delta-row>i em{position:absolute;top:-0.2rem;left:var(--ci-start);width:var(--ci-width);height:0.4rem;border-inline:1px solid #171717;background:rgba(23,23,23,0.35)}.delta-row>strong{font-size:0.76rem;text-align:right}.delta-baseline>i b{width:0.65rem;height:0.65rem;top:-0.32rem;background:#f4f1ea;border:1.5px solid #171717}.delta-sensori{border-top:1px solid rgba(23,23,23,0.18)}.delta-plot>p{padding-top:1rem;margin-bottom:0;border-top:1px solid rgba(23,23,23,0.2);color:#6d6a64;font-size:0.68rem;text-align:right}.delta-plot>p b{color:#171717}.results-cta{padding-block:clamp(6rem, 11vw, 11rem);background:#5544c4;color:#fffdf8}.results-cta-grid{display:grid;grid-template-columns:1.15fr 0.85fr;gap:clamp(3rem, 9vw, 10rem);align-items:end}.results-cta h2{max-width:10ch;margin-bottom:0}.results-cta-grid>div:last-child>p{max-width:32rem;margin-bottom:2rem;color:rgba(255,253,248,0.72);font-size:1.08rem}.results-cta-links{display:flex;gap:1.5rem;align-items:center;flex-wrap:wrap}.project-card{display:grid;grid-template-columns:minmax(0, 1.35fr) minmax(19rem, 0.65fr);gap:clamp(2rem, 5vw, 5rem);align-items:center}.project-card:nth-child(even){grid-template-columns:minmax(19rem, 0.65fr) minmax(0, 1.35fr)}.project-card:nth-child(even) .project-visual{order:2}.project-card:nth-child(even) .project-copy{order:1}.project-visual{position:relative;display:block;min-height:clamp(24rem, 48vw, 39rem);border-radius:2.25rem;color:#171717;text-decoration:none;overflow:hidden;transition:transform 300ms cubic-bezier(0.22, 1, 0.36, 1),border-radius 300ms ease}.project-visual:hover{transform:scale(0.985);border-radius:3rem}.project-card--coral .project-visual{background:#f47f64}.project-card--violet 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